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Top 5 Gaming Mouse with 4 Side Buttons

The good gaming mouse with side buttons can improve your performance in online games. Purchasing a high-quality mouse will not instantly transform you into an esports champion, but a responsive clicker with numerous customizable options can make your aim much more precise in team deathmatch games, for example. Gaming mice come in a range of sizes. Some are sleek and include bright RGB lights, while others are clunky and get right to the point. Whether you want flare or utility from your gaming mouse, we’ve curated a list that will suit a variety of budgets and gaming requirements.

Gaming Mouse with 4 Side Buttons

A mouse with only two buttons and a scroll wheel is insufficient for gaming purposes. You’d need a mouse that’s pleasant to use in the long term and has an adequate number of configurable side buttons. So, if you’re looking for the best gaming mouse with side buttons, we’ve got some excellent selections.

You can program side buttons on mouse to execute specific functions, giving you an advantage when gaming. For example, you can program one of the buttons to instantly reload your rifle, eliminating the need to reach for a specific key on the keyboard. You can also use the mouse’s specific buttons to perform backward and forward actions in other apps, such as browsers. If this seems useful to you, here are some of the finest gaming mouse with side buttons.

LTC Wireless Gaming Mouse

The LTC Wireless Gaming Mouse features wireless connectivity for comfortable use.

  • High DPI: 16,000 DPI ensures smooth and precise movement.
  • Ergonomic Design: The ambidextrous shape allows for comfortable use with either hand.
  • Lightweight (89 grams) for effortless hand mobility.
  • Compatible with multiple devices, including laptops and desktops.

ZEBRONICS High Precision Wired Gaming Mouse

  • Ergonomic design: Designed for both gaming and work, the ZEB-Uzi is a lightweight wired mouse that prioritises ergonomics to ensure a fatigue-free user experience.
  • Suitable for gaming: Elevate your gaming environment with the ZEB-Uzi mouse, which is known for its exceptional functionality, making it a top pick for improving your game experience.
  • DPI switch: This mouse has a dedicated DPI adjustment button and can operate at up to 2400 DPI, allowing you to choose the optimal sensitivity for your workflow.
  • Colorful LED lighting: Transform your gaming atmosphere with this mouse’s immersive Multicolor LED lights, which will improve your overall gaming experience.
  • Surface-friendly: Whether on a gaming mouse pad, a hardwood desk, or any other surface, this mouse provides consistent performance, allowing gamers to play without limitations.
  • Plug-and-play: The ZEB-Uzi gaming mouse comes with a sturdy 1.35-meter cord, offering an added layer of robustness to resist the rigours of gaming.

Corsair Sabre RGB Gaming Mouse

  • The Corsair Sabre RGB Gaming Mouse is another budget-friendly gaming mouse. One of its most notable qualities is its higher DPI range (for its pricing) of up to 10,000 DPI.
  • The 1000 Hz polling rate results in a highly sensitive mouse in your palms. At the same time, it’s lightweight and comfortable, and it should fit nicely in most people’s hands. The customizable lighting is a perk.
  • When compared to other mouse alternatives, this mouse appears to be slightly wider. On the plus side, all eight well-placed buttons are haptic enough to guide you through the RTS (Real-Time Strategy) games. Furthermore, you may always program them to perform specific functions. Fortunately, you will not be bothered with inadvertent clicking.
  • Unlike most mice, the DPI buttons are situated in the mouse’s upper-left corner, rather than below the scroll wheel. And the unique positioning makes it easy to modify the settings. After all, you must modify the index finger somewhat.
  • Unlike the mouse above, this one offers four-zone color backlighting that you may customize with the iCue software. Furthermore, the sturdy build ensures that the major switches and the entire mouse survive a long time.
  • However, the Sabre has one problem. It has a soft-touch texture and may lose grip if your palms sweat excessively while gaming.

SteelSeries Sensei 310

  • If you are searching for a fully ambidextrous mouse, the SteelSeries Sensei 310 is a wonderful choice. It’s a full-featured mouse with a bespoke sensor, an attractive design, and eight customizable buttons. This mouse’s ambidextrous design allows for two thumb buttons on either side.
  • Furthermore, the textured grips on the thumb rest and scroll wheel will help you control the mouse (and your games) more effectively. You may program all of the buttons and lighting to your liking.
    The lighting is unobtrusive and complements the mouse design. Currently, the Sensei 310 has two zones and multi-color RGB lighting.
  • Aside from that, many customers appreciate the proprietary TrueMove3 sensor’s precise tracking, ergonomic design, and performance.
  • Although it has a maximum DPI of 12,000, the mouse only has two DPI settings.
  • Furthermore, only one toggle allows you to swap between these options. The mouse appears to be solid and should last for a long time, but the connection cable is not braided.

Razer Viper V2 Pro


  • Max DPI: 6,400
  • Buttons: Gaming mouse with 4 side buttons
  • Size: 5.0 x 2.3 x 1.5 inches
  • Weight: 2.1 ounces

Reasons to Buy:

  • Super lightweight
  • Minimalist design.
  • Excellent battery life

Reasons to Avoid:

  • Plain appearance
  • Expensive for a gaming mouse

The $150 Razer Viper V2 Pro is marketed as a wireless esports mouse, but it is also suitable for general use. This is owing to the device’s lightweight, unassuming form and impressive battery life. A wealth of customization options via the Razer Synapse desktop app allow you to adjust the mouse’s operation to your preferences.

The Viper Pro 2 faces a high bar as the successor to the Razer Viper Ultimate. However, Razer aficionados can be confident that the Viper Pro 2 lives up to its predecessor and is worth the extra money over less expensive mice like the Razer Orochi.

Things to Consider When Purchasing a Gaming Mouse with Four Side Buttons

Button Customization Options

When choosing a gaming mouse, customizable buttons are an important consideration. Different games necessitate distinct activities, and having customizable buttons will give you an advantage in the game.
Most gaming mouse include at least a few customizable buttons, but others have more. Some mice even feature specialized macro buttons, which may be programmed to perform complex tasks with a single click.

DPI and Polling Rate

DPI sensitivity is an important feature to consider when selecting a gaming mouse. DPI, or dots per inch, is the number of pixels moved by the cursor on the screen for every inch the mouse moves physically. The higher the DPI sensitivity, the faster and more precisely the pointer moves. However, a high DPI sensitivity might result in jerky movements, making precision difficult.
The polling rate indicates how frequently the mouse broadcasts its position to the computer. The greater the polling rate, the more frequently the computer gets the mouse’s position, which leads to more responsive motions. A high polling rate is very useful in fast-paced games that need rapid reflexes.

Wired Vs Wireless

Wired and wireless gaming mice each have advantages and cons. Wired gaming mice provide a more solid and consistent connection, faster response times, and are less likely to interfere than wireless mice. They also do not require batteries or charging, making them more handy for long-term use. Wireless gaming mice allow you greater freedom of movement while also reducing desk clutter. They link to your computer via Bluetooth or a wireless receiver, allowing you to utilise them without being bound to your workstation. Wireless mouse are also extremely portable, making them ideal for travel. However, they require batteries or charging, which can be problematic if they are not charged.

Durability and Quality

When selecting a gaming mouse, it is important to evaluate its quality and longevity. Gaming mice are intended to last extended gaming sessions, thus they should be constructed from high-quality materials that can withstand wear and tear. Look for gaming mouse with long-lasting buttons and a sturdy design that can withstand frequent clicking and movement.

Frequently Asked Questions (FAQs)

Are all gaming mouse with 4 side buttons programmable?

Yes, you can program the side buttons on any mouse. However, only a few mouse types work with the brand’s official software. As a result, in some games, you may need to program the buttons using in-game options.

Is a gaming mouse with 4 side buttons ergonomic?

Not every mouse is ergonomic. If you want a mouse that won’t hurt your wrist, choose an ergonomic gaming mouse.

Can I use a mouse with side buttons on my Mac?

Yes, you can use mouse with side buttons on a Mac. However, you may not be able to use Mac programming software with all brands of mice. So, make sure the mouse maker provides an app for customizing the buttons on macOS.


Side buttons on a mouse can significantly improve a gamer’s performance by putting all of their frequently used options right at their fingertips, including DPI settings, macros, and other in-game commands.

Finding a good fit requires understanding your chosen gaming style and reviewing the features offered by some of the top gaming mice with side buttons listed above.



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